You can start your alcohol business in the dark colored neighborhoods only. There are four types of alcohol in total: Moonshiner (Whisky), Beer, Champagne and Canadian Whisky. You can select one of them in each of the four available neighborhoods, but only if you conquered them first.
Via the prohibition button on the right of your screen, you are able to manage your alcohol businesses, like: upgrade buildings, start or unload transports and sell goods.
You easily can navigate to the different types by the alcohol icons.